SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF SOME METAL IONS WITH 2-THIOACETIC-5-PHENYL-1,3,4- OXADIAZOLE

Authors

  • Hanan Ibraheem Department of Chemistry, College of Science, Al-Nahrain University, Baghdad-Iraq.
  • Hadeel Adel Department of Chemistry, College of Science, Al-Nahrain University, Baghdad-Iraq.
  • Ahmed Ahmed Polymer Research unit, College of Science, Al- Mustansiryah University, Baghdad-Iraq.
  • Nadia Salih Department of Chemistry, College of Science, Al-Nahrain University, Baghdad-Iraq.
  • Jumat Salimon School of Chemical Science & Food Technology, National University of Malaysia, Selangor D.E., Malaysia.
  • Abdualbasit Graisa School of Chemical Science & Food Technology, National University of Malaysia, Selangor D.E., Malaysia.
  • Yang Farina School of Chemical Science & Food Technology, National University of Malaysia, Selangor D.E., Malaysia.
  • Emad Yousif Department of Chemistry, College of Science, Al-Nahrain University, Baghdad-Iraq.

Keywords:

carboxylate, 1,3,4-oxadiazole, metal complexes, antimicrobial activity

Abstract

New metal complexes of the ligand 2-thioacetic-5-phenyl-1,3,4-oxadiazole with the metal ions Ni(II), Cu(II), Zn(II), Cd(II) and Sn(II) were prepared in alcoholic medium. The prepared complexes were characterized by FTIR Spectroscopy, electronic spectroscopy, mass spectroscopy 1H NMR, 13C NMR, magnetic susceptibility and conductivity measurements. From the spectral measurements, monomer structures for the complexes were proposed. Square planar geometry was proposed for the copper complex. The other complexes were proposed to be tetrahedral. Preliminary in vitro tests for antimicrobial activity show that all prepared compounds display good activity to Staphylococcus aureus, Escherishia coli, Pseudononas aeroginosa and Cndida albicans.

 

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Published

2010-03-01

Issue

Vol. 13 No. 1 (2010): March

Section

Articles

How to Cite

(1)
SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF SOME METAL IONS WITH 2-THIOACETIC-5-PHENYL-1,3,4- OXADIAZOLE. ANJS 2010, 13 (1), 43-47.

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