Oxidative Stress and antioxidants in Uterus Cancer Patients

Abstract

The present study was undertaken to assess oxidative stress by measuring the level of plasma malondialdehyde (MDA) and total thiol, and relate them to the level of some antioxidants such as p-carotene, vitamins (A, E & C), trace elements (Cu, Zn, & Se), albumin in plasma of uterus cancer patients before starting treatment and after remission.Blood specimens were taken from 20 newly diagnosed uterus patients. Only 10 patients of those were followed up.The results were compared with those obtained from 20 healthy individuals matching in age and sex.1'hc uterus cancer patients showed a significant reduction in plasma p-carotene, vitamins (A, E & C), albumin, total thiol, Zn, & Se. While plasma MDA, Cu & Cu / Zn ratios were significantly elevated.Ali above-mentioned parameters were normal or near to normal at remission.NON